Deramaxx Side Effects

By Hayley Harrison
Deramaxx is a flavored prescription medication used to treat the pain of osteoarthritis or discomfort after orthopedic surgery in dogs. Despite its effectiveness, Deramaxx poses a risk of side effects in some pets.


According to manufacturer clinical studies published on, dogs receiving the most common side effects of Deramaxx occur in less than 1 to 3 percent of dogs treated for osteoarthritis. Comparatively, as many as 10 percent of dogs given Deramaxx following surgery presented the common side effects.

Types of Common Side Effects

Common side effects of Deramaxx include vomiting, diarrhea, changes in stool color, changes in the frequency of drinking or urination, decreases in appetite, depression and listlessness.

Drug Interactions

Other drugs that relieve pain or inflammation such as aspirin, caprofen, etodolac and predisone increase your dog's risk of side effects from Deramaxx. Avoid combining these medications.


Infrequently, use of Deremaxx causes seizures in dogs. Collapsing or stupors are additional rare side effects of the drug.


If your dog has a history of gastrointestinal ulcers, kidney or heart disease, blood disorders, protein deficiencies or dehydration, your veterinarian may not prescribe Deramaxx due to its side effects.
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